Chris Willmott Profile picture
Jul 12, 2018 10 tweets 4 min read Twitter logo Read on Twitter
Second presentation on #ResearchMisconduct Alexander Wlodawer looking in detail at careless and rare fake structures in Crystallography and CryEM @FEBSnews
Wlodawer: several examples of structures deposited but not published, even many years later #ProteinStructure
Wlodawer: most notorious case of outright #Fabrication H.M. Krishna Murthy from University of Alabama retractionwatch.com/2018/04/10/inf…
Wlodawer: made three attempts to get editors (n=3) to retract a clearly erroneous structure - no response #PublicationEthics
Wlodawer: "successful" attempts to get retractions may include phrasing that says eg "this correction should note impact on the validity of other data in the paper"
Wlodawer: if you can remove the structure, and the rest of the paper is fine, then begs question why structure was in paper in first place #PublicationEthics
Wlodawer: #CryoEM emerging as important new technique, are the specialists in this field learning from the errors made in history of crystallography? #StructuralBiology
Wlodawer: people are claiming unrealistic resolution quality in #cryoEM maps
Wlodawer: there are also issues and inconsistency about whether the #cryoEM map/structure deposited is the original or sharpened data
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More from @cjrw

Jul 12, 2018
Fifth and final session on #ResearchIntegrity Brandon Stell on #PubPeer pubpeer.com @FEBSnews
Stell: Scientists are not the only people whose work relies on accuracy of published work - also basis for current and future research, public policy, etc #ResearchMisconduct
Stell: cites the #Poldermans case and how flawed publication that made its way into guidelines led to 8000 deaths
Read 13 tweets
Jul 12, 2018
Fourth speaker in #ResearchMisconduct session - Stefan Franzen "How not to design research misconduct policy" #FEBS2018
Franzen: Scientific funding has been dramatically shaken up by #InternationalPropertyRights and #TechnologyTransfer, incrementally since Bayh-Dole Act
Franzen: What happened to the *science* taking the lead in what gets published? #PublicationEthics
Read 11 tweets
Jul 12, 2018
Third #ResearchMisconduct presentation by Bernhard Rupp: The action is in the re(tr)action @FEBSnews #FEBS2018
Rupp breaks with convention and walks away from the podium #WanderingSpeaker
Rupp: valid concerns exist about incorrect and irreproducible research, but is there a "reproducibility crisis"? #ResearchMisconduct
Read 13 tweets
Jul 12, 2018
Last morning at #FEBS2018 - important session on #ResearchMisconduct #ResearchIntegrity getting underway
Laszlo Festus summarising the Transparency and Openness Promotion initiative cos.io/our-services/t… #ResearchEthics #PublicationEthics @FEBSnews
Festus moves on to outline #ALLEA Integrity Code of Conduct (which I also mentioned in my session on Monday) ec.europa.eu/research/parti… #Bioethics #FEBS2018
Read 6 tweets

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