Thread by @cjrw

Third #ResearchMisconduct presentation by Bernhard Rupp: The action is in the re(tr)action @FEBSnews #FEBS2018

Rupp breaks with convention and walks away from the podium #WanderingSpeaker

Rupp: valid concerns exist about incorrect and irreproducible research, but is there a "reproducibility crisis"? #ResearchMisconduct

Rupp: the phrase "almost always" is an important caveat given that science is based on empirical indicution #Bayesian @FEBSnews

He's also not afraid to use #ComicSans

Rupp: Cell-based experiments have intrinsic variability, structural data OUGHT to have better #Reproducibility

Rupp: Model likelihood ~ quality of error x prior probability
i.e. strong claims with little prior basis need especially strong evidence #ScientificMethod #FEBS2018

Rupp: #Fraud is "rational" and thus rarely a problem - true fabrications are almost always easy to detect. Real data have random errors and systematic errors

Rupp: Francis Bacon in 1620 recognised the difficulties of researchers will and emotions influencing data interpretation - this trap is not new

Rupp: do not assume #Maleficence if #Incompetence if an adequate explanation #ResearchConduct @FEBSnews

Rupp: Prevention is the objective - training should not just be techniques but include understanding of empirical reasoning, cognitive bias, etc

Rupp: Burden of proof needs to be on the claimant, not the critic

@threadreaderapp unroll thread please