Discover and read the best of Twitter Threads about #heartdisease
Most recents (2)
(Thread alert!) This review provides some extremely clear figures that explain not just why #LDL matters for #heartdisease but also HOW it matters | onlinejacc.org/content/72/10/… (1/10) 
First of all, it's never about what your LDL happens to be right now. It's about what you've been exposed to your whole life. Sometimes you see denialists cite cross-sectional studies (with no follow-up time) as evidence that LDL doesn't matter. This is why that's wrong. (2/10)
This is a very clear illustration how risk manifests over time. Most of us get CVD at some age - with lower lifetime exposure, you can push it further and further. Perhaps until you die of something else. (3/10)
1/ Important study on #antidepressants & #heartdisease. 6 months of Rx for even minor depression in #cardiac patients offers protection against adverse events (heart attack, death, etc) seen for many (8+) years out. bit.ly/2LBZPuM @JAMA_current # of interesting points...
2/ The effects of meds on mood were the same as those in many other studies, 2-3 points difference on symptoms, NNT to remission between 5 & 6, effect size under .4 …& this difference, often dismissed as minor, was associated with marked benefits in terms of overall health...
3/ it looks as if treating about 10 patients early on prevents one heart attack, w & other benefits for heart (& overall) health. Benefits were larger in those whose mood disorder remitted & those who completed the trial. So: good news. Brief inexpensive Rx w lasting benefits...
