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Right…there’s a study called “Futility of current urine salbutamol doping control” that is receiving some press today. It’s clearly related to the #Froome #salbutamol defense. I have some thoughts, and I’ll try to be brief, but apologies if this thread gets lengthy… (1/)
First, here’s a link to the study: bpspubs.onlinelibrary.wiley.com/doi/abs/10.111…
What they did is develop a pharmacokinetic model for salbutamol, and then ran 1000 simulations where a VIRTUAL subject inhales a dose of 800 mcg. The model then PREDICTS the urine concentration in those 1000 cases
What they did is develop a pharmacokinetic model for salbutamol, and then ran 1000 simulations where a VIRTUAL subject inhales a dose of 800 mcg. The model then PREDICTS the urine concentration in those 1000 cases
This is important because I suspect there’ll be some misunderstanding in coming weeks. This is NOT a study on human subjects that measures urine salbutamol to find a whole bunch of false positives. It’s a prediction in 1000 virtual subjects based on models built from known inputs
