Thread: Decreasing muscle mass in aging: The harmful effects and how to counteract ––

Tags: #sarcopenia #aging #ageing #HealthyAging #MSKover50 #resistance training, #weights #physicalmobility #muscle, #protein
#osteoporosis #bone #fracture #falls

Image: iofbonehealth.org/what-sarcopenia
Thread: 🔽muscle in #aging ––#Sarcopenia RX, prevention –––

#MSKover50 #resistance #physicalmobility #osteoporosis #bone #fracture #falls

Lifespan vs. Healthspan: Why We Need Muscle for #HealthyAging.
runnersworld.com/health-injurie…
+
Live Strong and Prosper...
link.springer.com/article/10.100…
Thread: Sarcopenia in #Aging: RX, prevention –––
🔽
Biochemical Pathways of #Sarcopenia &Their Modulation by Physical #Exercise: A Narrative Review
frontiersin.org/articles/10.33…
H/T @MathewPiasecki Tags: #MSKover50
LT: Key RE: onset & progress
RT: Rec. of @ACSMNews & @American_Heart
cont above.....#Sarcopenia #MSKover50 #aging
Altered signaling pathways…
♦️IGF-1
♦️TNF-a
♦️Myostatin
♦️Follistatin
♦️NAD+SIRT1,SIRT3
Leading to:
♦️Mitochondrial dynamics & biogenesis
♦️Protein degradation
♦️Protein synthesis
More info▶️frontiersin.org/articles/10.33…
Thread: #Sarcopenia in #Aging: RX, prevention–––
#MSKover50 #resistance #physicalmobility #osteoporosis #bone #fracture #falls
🔽
Dose of physical activity, physical functioning and disability risk in mobility-limited older adults: The LIFE study-RCT
Full: journals.plos.org/plosone/articl…
Thread: #Sarcopenia in #Aging: RX, prevention–––
#MSKover50 #resistance #physicalmobility #osteoporosis #bone #fracture #falls
From 1997–
sarcopenia.com/?m=199706
More than 20 yrs later, Americans r less fit, 🔼 BMI w/ more fat & less muscle. Choice: 🔼 healthy yrs or 🔼 sick yrs?
Cont, Sarcopenia in #Aging BGS Fall 2017 @GeriSoc :#Sarcopenia & Frailty

▶️ Definition

▶️ Community dwelling /67 yo! Incidence of #sarcopenia 4.6% men and 7.9% women! Lesson: Need early testing grip/ other strength

🔽 Grip strength assoc. w/ longer & more hospitalizations
More....Thread: Sarcopenia in #Aging
{from Brit MODIS Jan 2018:{Movement disorders in #ageing}
Speaker Miles Witham: #Sarcopenia, #Frailty & #HeartFailure ––
♦️knock on effects across multiple organ/ body systems
♦️absent other factors, frail w/same prognosis
cc #MSKAging
More...Thread: Sarcopenia in #Aging
Via Brit MODIS:Jan 2018 movement disorders in #ageing #aging
Symptom: Exercise Intolerance
Q: How much is due to #HeartFailure, how much to #sarcopenia?
{We know EX works with CHF}
Q: RX HF+Sarcopenia w/exercise rehabilitation too? #MSKAging
Thread: #Sarcopenia in #Aging: RX, prevention –
#MSKover50 #resistance #physicalmobility #osteoporosis #bone #MSKAging
🔽
Is #BMI An Indicator of A Healthy Weight? @ConversationEDU h/t @SandroDemaio
theconversation.com/we-asked-five-…
No. BMI doesn't distinguish fat vs muscle, more info 🔽
....RE: #BMI #Sarcopenia and #Aging and #Cognition/ #Dementia
Note phenomenon of 'Skinny Fat' –– looking thin but w/ little muscle, most is fat.
“Skinny Fat” in #OlderAdults May Predict #Alzheimers Risk neurosciencenews.com/skinny-fat-dem… @NeuroscienceNew
#MSKAging #GripStrength cc #AAIC18
Thread: #Sarcopenia in #Aging: RX, prevention
#MSKover50 #resistance #physicalmobility #osteoporosis #bone #MSKAging
#MuscleMass #BMI Vigorous #Exercise Is For All Ages/Stages
🔽
Sarcopenia – why you need to know what it is! Neat piece by @JulietMcGrattan
drjulietmcgrattan.com/2018/01/08/sar…
Thread: #Sarcopenia in #Aging
#MSKover50 #resistance #physicalmobility #osteoporosis #bone #MSKAging
MT @Brads_science
Is exercise a countermeasure 4aging? Can U help us?
In @FrontPhysiol, by myself, @DrLawrenceHayes, @HughesDC_Muscle &
Martin Burtscher- frontiersin.org/research-topic…
Just in case all this #Sarcopenia in #Aging seemed a bit much: Note 🔼muscle mass/strength brings incr.🔼 functional ability and 🔽 falls.
Look what grandma says:
Elderly Women Prefer Death to Suffering a #HipFracture
huffingtonpost.com/andrew-dudley/… Test all 65+:gait+strength. #MSKAging
........Perhaps quite sobering is the shocking statistic that 80 percent of women would prefer death than suffer a hip fracture and enter a nursing huffingtonpost.com/andrew-dudley/… via @HPLifestyle
Hear her interview.......
Tags: #Sarcopenia #MuscleMass #resistance training #MSKaging
Key: Test early ––in middle age, 50-70 ie #boomers BEFORE the last third of life when mom/dad/grandma/grandpa have already fallen. For #millennials + Gen X they need to exercise as if they're still in high school: adult sports, gym, on the trails and w/ weights. #100YearLifespan
Cont...#sarcopenia
QOL related to #fear of falling & #hipfracture in #olderwomen
bmj.com/content/320/72…
MQ"Nearly all women would trade off remainder life expectancy to avoid admission to a nursing home. 80% respondents said that they would rather be dead."

h/t @dementiarehab
More...Thread: #Sarcopenia in #Aging: RX, prevention
#MSKover50 #resistance #physicalmobility #osteoporosis #bone #MSKAging
#MuscleMass #BMI

MT @PhysioMeScience
Muscle as a paracrine and endocrine organ💪💪💪👀👀
sciencedirect.com/science/articl…
{NB:paywall}
More.....On #Sarcopenia, Muscle and Aging #MSKover50
MT @edelphysio
Nice table of best exercise and forms of #physicalactivity for #muscle function, #bone health & #balance. Resistance training & ball sports tops🏋️‍♂️ ⚽️
Full article 👉research-information.bristol.ac.uk/files/15970469…@CPNG_ISCP

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with Bernadette Keefe MD

Bernadette Keefe MD Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @nxtstop1

Mar 24, 2018
THREAD: The #MarchForOurLives via @AMarch4OurLives –– March 24, 2018
Information and twitter vignettes from around the world.
The major #MarchForOurLives via @AMarch4OurLives is in Washington, D.C
INFO: washingtonpost.com/news/dr-gridlo…
ROUTE: 🔽 Screenshot from excellent explainer video within the article
Via D.C. Metrorail: Metrorail Info @Metrorailinfo
Follow @wmata and @Metrorailinfo for updated information on Metro service before, during and after #MarchForOurLives #MarchForOurLivesDC #MFOLDC #wmata
How To Use The DC Metro freetoursbyfoot.com/use-washington… cc @AMarch4OurLives
Read 15 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Don't want to be a Premium member but still want to support us?

Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal

Or Donate anonymously using crypto!

Ethereum

0xfe58350B80634f60Fa6Dc149a72b4DFbc17D341E copy

Bitcoin

3ATGMxNzCUFzxpMCHL5sWSt4DVtS8UqXpi copy

Thank you for your support!

Follow Us on Twitter!

:(