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Jarred Younger up now. Neuroinflammation in #mecfs. We’ve all gotten inflammation diagnoses in the body (arthritis, e.g.) but never brain inflammation. Hard to diagnose! So how can we make that dx easier? (1/5) #pwme @MEActNet #MECFS18 
Hard to measure inflammation in a living person? Must be non-invasive, must be through and examine the whole brain. (2/5) #pwme @MEActNet #MECFS18
Microglia — bottom right is in an inflammatory state. Releases cytokines that cause ‘sickness behavior’. It makes you feel awful: that’s its job! Slow down to recover. (3/5) #pwme @MEActNet #MECFS18
The issue is that microglia can get primed so that a short walk can trigger the immune response. “That’s what we think is happening.” (4/5) #pwme @MEActNet #MECFS18
SO GLAD he included the myo-inositol information. I researched this pathway at Stanford. Myo-inositol is also activated during encephalopathy. (5/5) #pwme @MEActNet #MECFS18
Might be TOP RIGHT pls let's remember to check when livestream vid goes out!
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