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Will Watson Profile picture
Will Watson
@DrWillWatson
@royalpapworth cardiology clinical lecturer: heart failure and MRI @cambridgecardio / @rdmoxford research: cardiac metabolism and MRS @cuh_nhs governor
Aug 9, 2018 • 17 tweets • 8 min read
Tweetorial!
Troponin, troponinaemia, troponinitis, troponin leaks - distinguishing type 1 MI from type 2 or nonischaemic myocardial injury. Increased demand for a limited supply of evidence... Cardiac isoforms of Tn are expressed in cardiac muscle and released in various fragments on necrosis. Some troponin is unbound in cytoplasm – there is some disagreement over whether these free fragments ‘leak’ across the cell membrane under stress. heart.bmj.com/content/92/7/9…
Jul 31, 2018 • 18 tweets • 10 min read
Heart Failure with Preserved Ejection Fraction #HFPEF Tweetorial! Once thought as just diastolic dysfunction, it is much more than that!
(picture credit @Medcomic) #HeartFailure #CardioEd Why have we drawn a cut-off of 50% for rEF vs pEF? Well, this relates to older studies which showed that the risk of symptomatic heart failure increased significantly when your EF was less than 50%.
ahajournals.org/cgi/doi/10.116…