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@HeartOTXHeartMD

Study warns against combined use of oral #anticoagulants , #antiplatelet therapy for #AFib 1️⃣

#GARFIELD-AF registry

escardio.org/The-ESC/Press-…

2️⃣ Currently, do you stop #aspirin w #NOAC #DOAC for #AFIB in pts w previous history of stent (>1yr prior) for non-ACS CAD ? (Yes- I know it should be a less and less common scenario)

3️⃣ Currently, do you stop #aspirin w #NOAC #DOAC for #AFIB in pts w previous history of CAD ( #STEMI / #NSTE-ACS >1year prior) ?

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Akshay Khandelwal MD

@KhandelwalMD

Intro/10 #STEMI #tweetorial #FITSurvivalGuide for #ACCFIT. Organized by @dr_chirumamilla. @ACCCardioEd @ACCinTouch

@BraunwaldEugene

1/10 #STEMI from ruptured plaque, less plaque erosion. @BraunwaldEugene pic demonstrates LDL oxidized, glycated➡️cytokines release express adhesion molecules➡️monocytes roll, diapedesis➡️ingest LDL, become foam cell➡️SMC migrate, proliferate➡️some apoptosis➡️plaque

2/10 Why #STEMI on #ECG
1. Diastolic current of injury: current away from relatively depolarized injury➡️TQ depression➡️normalized on ECG➡️ST elevation
2. Systolic current of injury: current towards injury due to early repol➡️ST elevation

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