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Interested in thinking more deeply about what a “cause” is? Causation: A Very Short Introduction from @ranilillanjum and @SDMumford is a great starting point.
Thread recap starting now👇🏽#twittereview #epibookclub #causation #causalinference #epimethodsclub
Thread recap starting now👇🏽#twittereview #epibookclub #causation #causalinference #epimethodsclub
Chapter 1 sets up the problem: causation is hard to define, both in general & for specific events. It’s more than just temporal ordering, but is it a separate thing?
An ex., a town gets sick after flood of rats. Did the rats cause sickness? Maybe it was actually a sick visitor.
An ex., a town gets sick after flood of rats. Did the rats cause sickness? Maybe it was actually a sick visitor.
Chapter 2 introduces us to Hume’s theories of causation.
1st, regularity: sometimes things are *regularly* followed by other things.
Is this causation? If so, how regular is regular enough? How many times do we have to observe steam after heating water to say it’s causal?
1st, regularity: sometimes things are *regularly* followed by other things.
Is this causation? If so, how regular is regular enough? How many times do we have to observe steam after heating water to say it’s causal?
Now that the #epibookclub is over, my weekends are free for reading #RCTs. So, how about a #tweetorial about #pragmatic trials, causal questions, and #landmark analyses, inspired by the #SCOTHEART trial?
#epimethodsclub #cardiotwitter
#epimethodsclub #cardiotwitter
If we’re going to talk about #pragmatic trials, then we need to start with a definition. The simplest definition I’ve seen is from a trialist I interviewed for my recent @JClinEpi paper (authors.elsevier.com/a/1XS1b3BcJPuv…)
pRCTs “...attempt to address effectiveness in real world settings”
pRCTs “...attempt to address effectiveness in real world settings”
Sure, it’s a bit vague but it’s useful because, like Tolstoy’s unhappy families, #pragmatic trials are all different.
So, what makes me think #SCOTHEART is pragmatic?
My 2¢: lack of blinding, inclusion criteria based on symptoms not diagnoses, & standard care as comparator.
So, what makes me think #SCOTHEART is pragmatic?
My 2¢: lack of blinding, inclusion criteria based on symptoms not diagnoses, & standard care as comparator.
