Discover and read the best of Twitter Threads about #epibookclub

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Interested in thinking more deeply about what a “cause” is? Causation: A Very Short Introduction from @ranilillanjum and @SDMumford is a great starting point.

Thread recap starting now👇🏽#twittereview #epibookclub #causation #causalinference #epimethodsclub
Chapter 1 sets up the problem: causation is hard to define, both in general & for specific events. It’s more than just temporal ordering, but is it a separate thing?

An ex., a town gets sick after flood of rats. Did the rats cause sickness? Maybe it was actually a sick visitor.
Chapter 2 introduces us to Hume’s theories of causation.

1st, regularity: sometimes things are *regularly* followed by other things.

Is this causation? If so, how regular is regular enough? How many times do we have to observe steam after heating water to say it’s causal?
Read 23 tweets
Now that the #epibookclub is over, my weekends are free for reading #RCTs. So, how about a #tweetorial about #pragmatic trials, causal questions, and #landmark analyses, inspired by the #SCOTHEART trial?

#epimethodsclub #cardiotwitter
If we’re going to talk about #pragmatic trials, then we need to start with a definition. The simplest definition I’ve seen is from a trialist I interviewed for my recent @JClinEpi paper (authors.elsevier.com/a/1XS1b3BcJPuv…)

pRCTs “...attempt to address effectiveness in real world settings”
Sure, it’s a bit vague but it’s useful because, like Tolstoy’s unhappy families, #pragmatic trials are all different.

So, what makes me think #SCOTHEART is pragmatic?

My 2¢: lack of blinding, inclusion criteria based on symptoms not diagnoses, & standard care as comparator.
Read 20 tweets
Wow, #epibookclub, we’re officially halfway through the #bookofwhy!

Chapter 6 is a doozy... we’re going to learn all about paradoxes!! Get ready to have your mind blown!! 🤯🤯🤯
Given last week’s tragic fail on paradox gifs, I made you our very own #epibookclub gif! It’s paradox time!!

(Please be kind this is my very first homemade gif 😂😂)
I like the chapter set up this week: @yudapearl explains importance of spending time working out the paradoxes...they can give us insight into how people process causal information. He says these are paradoxes b/c they straddle the rungs of the #ladderofcausation

So, up we go!
Read 25 tweets

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